Akụkọ

Na 1968, Kruger-Theimer gosipụtara otu esi eji ụdị ọgwụ pharmacokinetic emepụta usoro ọgwụgwọ dị irè. Usoro Bolus, Elimination, Transfer (BET) a nwere:

dose bolus agbakọrọ iji mejupụta akụkụ etiti (ọbara) ahụ,

ntinye ọnụego mgbe niile nke hà nhata ọnụego mwepụ,

ọgwụ nke na-akwụghachi ụgwọ maka mbufe na anụ ahụ dị n'akụkụ: [ọnụego na-ebelata nke ukwuu]

Usoro ọdịnala gụnyere ịgbakọ usoro ọgwụ propofol site na usoro Roberts. A na-esochi usoro ibu 1.5 mg/kg wee tinye 10 mg/kg/hour nke a na-ebelata ka ọ bụrụ 8 na 6 mg/kg/hour na nkeji iri.

Nzube ebe mmetụta

Mmetụta bụ isi nkeọgwụ mgbuỌgwụ ndị a na-eji n'ime akwara bụ mmetụta ndị na-eme ka ahụ ghara iru ala ma na-eme ka mmadụ ghara inwe mmetụta, ebe ọgwụ ahụ na-arụkwa ọrụ bụ ụbụrụ. Ọ dị mwute ikwu na ọ gaghị ekwe omume n'ọrụ ahụike ịtụle mkpokọta ụbụrụ [ebe mmetụta]. Ọ bụrụgodị na anyị nwere ike ịtụ mkpokọta ụbụrụ kpọmkwem, ọ ga-adị mkpa ịmata kpọmkwem mkpokọta mpaghara ma ọ bụ ọbụna mkpokọta ndị na-anabata ya ebe ọgwụ ahụ na-arụ ọrụ ya.

Inweta njupụta propofol mgbe niile

Ihe osise dị n'okpuru na-egosi ọnụego ọgwụ a chọrọ na ọnụego mbelata nke ukwuu mgbe ejiri ọgwụ bolus mee ihe iji nọgide na-enwe njupụta propofol n'ọbara mgbe niile. Ọ na-egosikwa oge dị n'etiti njupụta ọbara na ebe mmetụta ahụ.